Transgenic mice for monoclonal, bispecific, and multispecific antibody discovery.
Translational data from PDX, cell lines, humanized CD34+/PBMC mice, and genetically engineered models.
Test optimal dosage and cytokine response based on unique PBMC profiles.
Increasingly, antibodies are being engineered to improve safety, efficacy, and clinical success. JAX provides humanized mice that support every stage of preclinical development, from PK to toxicity.
